Anti-Alcohol Antioxidants with HepatoProtection Complex is an improved formula containing additional antioxidants designed to suppress free radicals, neutralize toxic alcohol metabolites such as acetaldehyde,32-35 and support healthy liver function. In addition to vitamin B1, vitamin C, N-acetyl-cysteine and benfotiamine, this formula’s HepatoProtection Complex provides therapeutic doses of these novel antioxidants:
• Chlorophyllin — an agent that protects the body from oxidative stress36-38
• Leucoselect® grapeseed extract, silymarin (from milk thistle), and resveratrol — three hepatoprotective agents that aid in reducing compounds from potentially toxic xenobiotics and protecting cells from free radical-induced oxidative stress39-41
• Picroliv® Picrorhiza kurroa root extract — contains antioxidant kutkin that scavenges alcohol-induced excess free radicals, and stimulates regeneration of cells (hepatocytes)42
• Barley grass powder extract — enhances the enzyme aldehyde dehydrogenase, thus inhibiting the formation of acetaldehyde malondialdehyde43
Consuming alcoholic beverages results in the generation of free radicals. People who drink a lot of alcohol often suffer because of massive free radical-induced cellular damage. Alcohol-induced free radical assault can wreak short-term havoc throughout the body, and these same damaging free radicals are associated with accelerated aging.
Reactive oxygen species (ROS) have been associated with acute ethanol-induced liver damage. A study published in the journal Artery confirmed a specific toxic metabolite of alcohol (acetaldehyde) and identified an antidote (N-acetyl-cysteine): “All known pathways of ethanol metabolism result in the production of acetaldehyde, a highly reactive compound. N-acetyl-cysteine (NAC), an analogue of the dietary amino acid cysteine, binds acetaldehyde, thus preventing its damaging effect on physiological proteins.”29 NAC is a glutathione precursor and direct antioxidant. Pretreatment with or co-administration of NAC helps to inhibit acute ethanol-induced liver damage via counteracting ethanol-induced oxidative stress.30,31 NAC also attenuates the progression of the abnormal retention of lipids within liver cells by decreasing development of oxidative stress and subsequent increases in TNF-alpha.
Thus, when people are exposed to a known toxic substance such as alcohol, it makes perfect sense to take a proven antidote — namely, antioxidants.
Taking the proper supplements before and after drinking can substantially protect liver cells from the free-radical damaging effects of alcohol consumption.