Benfotiamine, a fat-soluble form of vitamin B1 (thiamine), supports healthy blood sugar metabolism and helps protect the body’s tissues against advanced glycation end products and oxidative stress.13 For example, the enzyme transketolase is critical to blood sugar metabolism. Like many enzymes, transketolase requires a co-factor. In this case, it needs assistance from thiamine. Unfortunately, thiamine is water-soluble, which makes it less available to the interior of the cell. Benfotiamine is fat-soluble and can easily penetrate into the inside of cells. It is also more bioavailable than the water-soluble thiamine.
In a landmark study, benfotiamine effectively increased transketolase activity in cell cultures by an astounding 300%, compared to a mere 20% for thiamine. This robust activation was sufficient to block three of the four major metabolic pathways leading to blood vessel damage.14 Benfotiamine also blocks the activation of the transcription factor known as nuclear factor-kappa B (NF-kB), which is implicated in numerous inflammatory conditions.13
Overall, benfotiamine can activate glucose metabolism and promote already healthy blood glucose levels. It can also reduce formation of advanced glycation end products to prevent glucose toxicity and correct endothelial cell defects caused by high concentrations of blood glucose, especially inside endothelial, retinal, kidney and nerve cells. Benfotiamine also helps maintain healthy endothelial function.15-21 Benfotiamine with thiamine is a low-cost dietary supplement that can help maintain already-normal blood sugar levels and support the health of the nerves, kidneys, eyes, blood vessels, and heart.
*Percent Daily Values are based on the 2000 Calorie Diet. Your daily values may be higher or lower depending on your calorie needs. **Daily value not established.
Other Ingredients: microcrystalline cellulose, vegetable capsule, silica, magnesium stearate.
Contains no: milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.
Directions: Take one capsule four times daily with or without food, or as recommended by a healthcare practitioner. If using Mitochondrial Energy Optimizer or Super Carnosine, only two to three capsules daily are needed to reach the optimal dose of 400 mg daily.
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The majority of the product information has been reprinted from the manufacturer.