Cranberries are a well-known source of abundant flavonoids and other bioactive components. There are several distinct classes of flavonoids found in cranberries, all with antioxidant properties and each having potentially unique physiologic functions. Cranberry flavonoids include anthocyanins, the pigments that give cranberries their rich red color, flavonols, and proanthocyanidins. Of particular interest to researchers, proanthocyanidins isolated from cranberries exhibit an anti-adhesion effect. This anti-adhesion effect is the mechanism by which cranberries help maintain urinary tract health. Cranberry proanthocyanins are easily absorbed by the digestive tract and excreted in the urine. The presence of these compounds in the urine helps to cleanse the waste stream.*
D-Mannose is a simple sugar that occurs naturally in some plants. Although small amounts of D-Mannose are metabolized by the human body, most of it is rapidly excreted in the urine. Similar to proanthocyanins, it exerts an anti-adhesion effect in the urinary tract that allows waste products to be flushed out in the urine. Because insubstantial amounts of D-Mannose are used by the body, it does not interfere with healthy blood sugar regulation. This dual anti-adherence formula also contains probiotic bacteria that help to maintain healthy microbial balance.*
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