Pterostilbene is a natural substance found in blueberries and other plants. Pterostilbene and resveratrol are both stilbene compounds. Their chemical structure is closely related, as are their functions. When used together, these two compounds may have a complementary effect and help to activate our longevity genes.
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• May help support a healthy lifespan
• May help support healthy cell division and replication
• May help promote healthy cholesterol levels already within normal range
• May help support healthy insulin function/glucose metabolism
• May help relieve common, everyday inflammation caused by a number of lifestyle factors
• May help promote healthy cognitive performance
Specifically, scientists have found that resveratrol activates genes near the beginning of the molecular cascade affecting lifespan, while Pterostilbene directly activates genes further down from the sites of resveratrol's action. Genceutic Naturals pTeroBlue™ + Resveratrol uses Advanced Blueberry Complex standardized to provide Natural Identical 99% pure, trans-pterostilbene and 98% trans-resveratrol.
In addition to their affects upon lifespan, stilbenes (including pterostilbene and resveratrol) have diverse biochemcial activities, which include supporting healthy cell-division and replication, promoting healthy cholesterol levels already within and normal range and supporting healthy insulin function/glucose metabolism. For example, pterostilbene modulates genes that help the body avoid abnormal cell division and eliminate those cells that may have already replicated poorly. Pterostilbene also naturally affects the expression of genes that activate fat-sensing complexes and was found to favorably affect lipid/cholesterol profiles in animal research.
In the liver, pterostilbene favorably modifies several vital glucose-regulating enzymes, which helps to control blood sugar. In also reduces markers of dangerous glucose-protein complexes called glycosylated proteins. In addition, pterostilbene may also have a positive impact upon common, everyday inflammation caused by a number of lifestyle factors, as well as promoting healthy cognitive performance.
Research has also shown that resveratrol significantly extends the lifespan of short-lived fish and mice. Human clinical research has shown that resveratrol has potent antioxidant effects and was able to help reduce the presence inflammatory chemicals in the body, leading to an anti-inflammatory effect. In addition, resveratrol helps modulate the Sirt 1 gene , which was shown in research to protect mice against diet-induced-weight and insulin resistance and improve glucose balance.