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Brand: Doctor's Best     Categories: Anxiety / SAMe


SAMe 200mg











Doctor's Best

SAMe 200mg







SAMe 200mg

SAMe 200mg  60  Tablet

Supplement Facts

Serving Size: 1 Tablet

Amount per
% Daily*

S-Adenosyl Methionine
(from 400 mg of SAM-e tosylate disulfate)




**Daily value not established.

Other Ingredients:
Cellulose gel, methacrylic acid copolymer, comprtol 888ATO, talc, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silica, medium chain triglycerides, sodium starch glycolate and iron oxide.

Suggested Adult Use:
Take 1 tablet daily away from food, or as directed by a health care professional. Do not chew or crush tablet.

Warnings: Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

Suitable for vegetarians. Contains nothing other than listed ingredients


Doctor's Best SAMe 200 contains 200 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.

S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

Supplementing with SAMe

The manufacturing process of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in SAMe 200 is processed to yield the highest available percentage of the active pure S,S form on the market.

SAMe and Joint Function

SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.*

SAMe and Neural Health

SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.*

SAMe and Liver Function

SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.*




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*Statements on this site have not been evaluated by the Food and Drug Administration. 
Products on this site are not intended to diagnose, treat, cure, or prevent any disease. 
Prices are subject to change at anytime and without notice. 
The majority of the product information has been reprinted from the manufacturer.